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Chemical Name: 1-(1-(1-(ethylsulfonyl)piperidin-4-yl)ethyl)-N-((4-methoxy-6-methyl-2-oxo-1
Carfilzomib was dosed to mice/rats by intravenous administration at 0
InChiKey: LXFKEVQQSKQXPR-UHFFFAOYSA-N
is a potent inhibitor of β-catenin-responsive transcription (CRT) that inhibits Wnt signaling in a reporter assay in vitro (IC50 = 40
PMA (100 nM)
BPTES - CAS# 314045-39-1 size:10mg solid Chemical Name: 1-(1-(1-(ethylsulfonyl)piperidin-4-yl)ethyl)-N-((4-methoxy-6-methyl-2-oxo-1BPTES, CAS No. 314045 39 1, is a selective inhibitor of Glutaminase GLS1 (KGA), which is found in the kidney and brain, and is positively regulated by myc and strongly expressed in many tumors and tumor cell lines. BPTES has a K(i) of approx. 3 microM. BPTES inhibits the allosteric activation caused by phosphate binding and promotes the formation of an inactive complex. Product information CAS Number: 314045 39 1 Molecular Weight: 524. 68 Formula: