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SNS-032 activity is readily reversible
small-molecule inhibitor of JAK2
α2b- and α2c-adrenergic
CC1=CC(=CC2=NN=C(NC3C=CC(=CC=3)OCCN3CCCC3)N=C21)C1=CC(=CC=C1Cl)OC(=O)C1C=CC=CC=1
Molecular Weight: 1486
Argatroban SK-3 inhibitor 1 SNS-032 activity is readily reversibleArgatroban is an anticoagulant that is a direct thrombin inhibitor. Argatroban was approved in 2000 for prophylaxis or treatment of thrombosis in patients with heparin induced thrombocytopenia (HIT). Argatroban is a direct thrombin inhibitor that reversibly binds to the thrombin active site. Argatroban exerts its anticoagulant effects by inhibiting thrombin catalyzed or induced reactions, including fibrin formation; activation of coagulation factors
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