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AZD4547 ustat Mijatovic T

SKU: 90871984937

4.1
USD96.00 USD121.00

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Description

Mijatovic T

Smiles: C[C@@H]1O[C@@H](OC[C@H]2O[C@@H](OCCC3C=C(O)C(O)=CC=3)[C@H](O)[C@@H](O[C@@H]3O[C@@H](C)[C@H](O)[C@@H](O)[C@H]3O)[C@@H]2OC(=O)/C=C/C2=CC(O)=C(O)C=C2)[C@H](O)[C@H](O)[C@H]1O

Celastrol induces apoptosis in RPMI-8226 cells indicated by the activation of caspase-8

8-naphthyridine-1(2H)-carboxamide

Desai-Krieger D

AZD4547 ustat Mijatovic TAZD4547 is an orally bioavailable inhibitor of the fibroblast growth factor receptor (FGFR) with potential antineoplastic activity. FGFR inhibitor AZD4547 binds to and inhibits FGFR, which may result in the inhibition of FGFR related signal transduction pathways, and, so, the inhibition of tumor cell proliferation and tumor cell death. FGFR, up regulated in many tumor cell types, is a receptor tyrosine kinase essential to tumor cellular proliferation,

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