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Efinaconazole inhibits fungal lanosterol 14α-demethylase involved in the biosynthesis of ergosterol
CAS Number: 1081110-72-6
Formula: C25H34N2O5
The mean 50% inhibitory concentration (IC50) and the standard error of the mean (SEM) are calculated via nonlinear regression
7-dihydroxy-2-(4-hydroxyphenyl)-5-methoxy-8-(3-methylbut-2-en-1-yl)-4H-chromen-4-one
Pristinamycin 21278 Efinaconazole inhibits fungal lanosterol 14α-demethylasePristinamycin, produced by Streptomyces pristinaespiralis, is an orally active streptogramin like antibiotic consisting of two chemically unrelated components: Pristinamycin I (PI) and Pristinamycin II (PII). Pristinamycin is highly active against many antibiotic resistant pathogens, particularly Gram positive bacteria, including Methicillin resistant Staphylococcus aureus (MRSA), Vancomycin resistant S. aureus (VRSA) and Enterococcus faecium (VREF).
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