Hydroxy-Dynasore Catalog No.:M25683-C 33)/t25-/m0/s1

33)/t25-/m0/s1

CAS Number: 853929-59-6

Smiles: NC(=O)C1=CN=C(NCCC2=CC(Cl)=C(O)C=C2)N=C1NCC1C=CC=CC=1

C2HF3O2/c1-2-3-15-52(81-60(95)40-88-23-19-47(20-24-88)80-59(94)39-89-25-27-90(41-61(96)97)29-31-92(43-63(100)101)32-30-91(28-26-89)42-62(98)99)65(103)87-57-36-58(93)76-21-10-9-17-51(64(72)102)82-68(106)55(34-46-37-78-50-16-8-7-14-49(46)50)85-66(104)53(18-11-22-77-71(73)74)83-67(105)54(33-45-12-5-4-6-13-45)84-69(107)56(86-70(57)108)35-48-38-75-44-79-48

InChi: InChI=1S/C56H78N16O13/c1-5-31(4)46(71-50(79)40(22-33-15-17-36(73)18-16-33)67-52(81)45(30(2)3)70-48(77)38(13-9-19-62-56(58)59)65-47(76)37(57)25-44(74)75)53(82)68-41(23-34-26-60-28-63-34)54(83)72-20-10-14-43(72)51(80)66-39(21-32-11-7-6-8-12-32)49(78)69-42(55(84)85)24-35-27-61-29-64-35/h6-8

Hydroxy-Dynasore Catalog No.:M25683-C 33)/t25-/m0/s1Hydroxy Dynasore (Dyngo 4a), a structural analog of Dynasore (HY 15304), is an potency improved, low cytotoxicity and nonspecific binding dynamin inhibitor with IC50 values of 0. 38 M and 2. 3 M for brain dynamin I and recombinant rat dynamin II, respectively. Hydroxy Dynasore inhibits dynamindependent endocytosis of transferrin with an IC50 of 5. 7 M in vitro. Product information CAS Number: 1256493 34 1 Molecular Weight: 338. 31 Formula: C18H14N2O5