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MC-Val-Ala-PAB-PNP - CAS# 1639939-40-4 0179 PubMed Central PMCID: PMC6394573

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Description

PubMed Central PMCID: PMC6394573

¹⁶]hexadec-10-ene-3

hSMG-1 kinase plays a dual role in a highly conserved RNA surveillance pathway termed nonsense-mediated RNA decay (NMD) and in cellular genotoxic stress response

Smiles: CC1C(=CC=CC=1O)C(=O)N[C@@H](CSC1C=CC=CC=1)[C@H](O)CN1C[C@H]2CCCC[C@H]2C[C@H]1C(=O)NC(C)(C)C

InChi: InChI=1S/C20H17NO6/c1-21-5-4-10-6-14-15(25-8-24-14)7-12(10)17(21)18-11-2-3-13-19(26-9-23-13)16(11)20(22)27-18/h2-3

MC-Val-Ala-PAB-PNP - CAS# 1639939-40-4 0179 PubMed Central PMCID: PMC6394573MC Val Ala PAB PNP is a cleavable ADC linker used in the synthesis of antibody drug conjugates (ADCs). Product information CAS Number: 1639939 40 4 Molecular Weight: 651. 66 Formula: C32H37N5O10 Synonym: MC Val Ala PABC PNP Chemical Name: {4 [(2S) 2 [(2S) 2 [6 (2,5 dioxo 2,5 dihydro 1H pyrrol 1 yl)hexanamido] 3 methylbutanamido]propanamido]phenyl}methyl 4 nitrophenyl carbonate Smiles:

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