Piceatannol - CAS# 10083-24-6 035TING-Inducer-1 2-d]pyrimidine-6-acrylamides bearing additional solubilizing functions

2-d]pyrimidine-6-acrylamides bearing additional solubilizing functions

1-14H3/t20-

17)18/h2-3

It causes cell death through the apoptosis pathway

in non-small cell lung cancer cell lines

Piceatannol - CAS# 10083-24-6 035TING-Inducer-1 2-d]pyrimidine-6-acrylamides bearing additional solubilizing functionsPiceatannol is a selective inhibitor of protein tyrosine kinase Syk. It could inhibit ICa, L, Ito, IKr, Ca2+ transients and Na+ Ca2+ exchange except IK1. Shows multiple biological activities such as anti inflammatory, antiproliferative and immunomodulatory effects. In vitro: The treatment of human myeloid cells with piceatannol suppressed TNF induced DNA binding activity of NF B. The effect of piceatannol was not restricted to myeloid cells, as TNF