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CBR-5884 nib (EGF816) 1415716-58-3

SKU: 99646245035

4.7
USD100.00 USD127.00

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Description

1415716-58-3

is α7 nicotinic acetylcholine receptor positive allosteric modulator

5-dihydro-1H-imidazol-2-olate

Gardiquimod: a Toll-like receptor-7 agonist that inhibits HIV type 1 infection of human macrophages and activated T cells

for 2 days) decreases the level of MYCN protein in MYCN-amplified neuroblastoma xenografts

CBR-5884 nib (EGF816) 1415716-58-3CBR 5884 is an active, selective inhibitor of phosphoglycerate dehydrogenase (PHGDH) with an IC50 of 33 M. CBR 5884 inhibits de novo serine synthesis in cancer cells and is selectively toxic to cancer cell lines with high serine biosynthetic activity. CBR 5884 selectively inhibits the proliferation of melanoma and breast cancer lines that have a high propensity for serine synthesis. Product information CAS Number: 681159 27 3 Molecular Weight: 336. 39

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