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Tirapazamine is activated to its toxic form preferentially in the hypoxic areas of solid tumors
PP-121 could restore actin stress fiber staining in NIH3T3 cells transformed with v-Src(Thr338)
InChiKey: NIDZYXQFQSHBTG-WATAJHSMSA-N
CAS Number: 594839-88-0
The inhibitory activity of KW-2449 is not affected by the presence of human plasma protein
(S, R, S)-AHPC TFA - CAS# 1631137-51-3 Size:2mg solid Tirapazamine is activated to its(S, R, S) AHPC TFA (VH032 NH2 TFA) is the VH032 based VHL ligand used in the recruitment of the von Hippel Lindau (VHL) protein. (S, R, S) AHPC TFA can be connected to the ligand for protein (e. g., BCR ABL1) by a linker to form PROTACs (e. g., GMB 475). GMB 475 induces the degradation of BCR ABL1 with an IC50 of 1. 11 M in Ba F3 cells. Product information CAS Number: 1631137 51 3 Molecular Weight: 544. 59 Formula: C24H31F3N4O5S Synonym: VH032 NH2 TFA