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over a period of 21 days) exhibits robust in vivo efficacy in two Pim kinases driven tumor models
Epirubicin is favoured over doxorubicin
14R)-6-(((2S
Smiles: C[C@@H](CC)[C@H](/N=C(\O)/[C@H](CCC(O)=O)/N=C(\O)/[C@@H](/N=C(\O)/[C@H](CCC(=N)O)/N=C(\O)/[C@@H](N)CCCCN)[C@@H](C)CC)/C(/O)=N/[C@@H](CCCCN)/C(/O)=N/[C@@H](CCCCN)/C(/O)=N/[C@@H](CC1C=CC=CC=1)/C(/O)=N/[C@@H](CCCCN)C(O)=O
InChi: InChI=1S/C57H79N13O12S2/c1-3-40-51(76)66-47(57(82)68-49(34(2)72)50(59)75)33-84-83-32-46(67-53(78)43(27-35-11-5-4-6-12-35)61-48(74)31-70-23-21-69(22-24-70)25-26-71)56(81)64-44(28-36-16-18-38(73)19-17-36)54(79)65-45(29-37-30-60-41-14-8-7-13-39(37)41)55(80)63-42(52(77)62-40)15-9-10-20-58/h4-8
AT-121 droxy-3-methoxybenzaldehyde over a period of 21AT 121 is a bifunctional nociception and mu opioid receptor agonist, with Kis of 3. 67 and 16. 49 nM, respectively. AT 121 is a safe, non addictive analgesic, and shows antinociceptive and antiallodynic effects. Product information CAS Number: 2099681 31 7 Molecular Weight: 462. 65 Formula: C24H38N4O3S Chemical Name: N (2 {3 oxo 1' [4 (propan 2 yl)cyclohexyl] 2,3 dihydro 1H spiro[isoquinoline 4,4' piperidin] 2 yl}ethyl)aminosulfonamide Smiles:
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