S-(+)-Rolipram suppresses LPS-induced TNFα expression from human monocyte through inhibiting PDE4 with IC50 about 2 μM
16-31)21(26)10-11-29(22
as well as the cyclin D1 protein expression
InChi: InChI=1S/C20H23N3O3/c1-22(2)11-17-18(25-4)8-13(9-19(17)26-5)16-12-23(3)20(24)15-10-21-7-6-14(15)16/h6-10
InChiKey: CZYWHNTUXNGDGR-UHFFFAOYSA-L
Estradiol benzoate 3258 analog S-(+)-Rolipram suppresses LPS-induced TNFα expressionEstradiol Benzoate ( Estradiol 3 benzoate), a prodrug of estradiol, acts as a steroid sex hormone. It exhibits mild anabolic and metabolic properties, and increases blood coagulability. Product information CAS Number: 50 50 0 Molecular Weight: 376. 49 Formula: C25H28O3 Synonym: Estradiol 3 benzoate 17 Estradiol 3 benzoate Chemical Name: (1S,3aS,3bR,9bS,11aS) 3a,3b,9b trihydrogenio 1 hydroxy 11a methyl 1H,2H,3H,3aH,3bH,4H,5H,9bH,10H,11H,11aH