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CAS Number: 1433953-83-3
56 μM (M109c)
Chemical Name: hexasodium (1R
InChiKey: AXRUEPFPTQYHQD-UHFFFAOYSA-N
AMG 487 is a potent and selective antagonist of chemokine (C-X-C motif) receptor 3 (CXCR3) with IC50 values of 8nM and 8
BDA-366 Size:Contact [email protected] for quotation CAS Number: 1433953-83-3BDA 366 is a selective antagonist of BCL2 BH4 domain with Ki value of 3. 3 nM . BCL2 is an important anti apoptotic protein. BCL2 homology 4 (BH4) domain is required for its antiapoptotic function, thus acts as a promising anticancer target . BDA 366 is a selective BCL2 inhibitor. BDA 366 induced conformational change of BCL2 that exposed the BH3 domain, resulting in abrogation of its prosurvival function and conversion of BCL2 to a prodeath protein.
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