You could probably beat some mono-white pile with Sanctifier since none of their other cards matter, but the fact it just shows up as the cherry on top of one of the best decks in the format that already presents a ton of other issues and can freely recast Sanctifier off Lurrus of the Dream-Den is a bit too much to handle
Core Strategy: Deploy efficient, low-to-the-ground lifelink threats early like Vampire of the Dire Moon, Gifted Aetherborn, and Vampire Nighthawk to establish a solid early defense and pad your life total
Miles powers up others and then transforms into a camouflaging web-slinger with first strike and haste
I guess that pushes us along to the sideboard
Use these self-damaging cards, alongside powerful creatures like Archon of Cruelty or Hullbreaker Horror who can either be cast for free using Rona, Tolarian Obliterators effect, or discarded and reanimated after being dumped into the graveyard by Rona, Herald of Invasion