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Nesland JM
Smiles: C=C[C@@H]1[C@@H]2CC(O)OC(=O)C2=CO[C@H]1O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O
2-oxazole-5-carboxamide
Ezetimibe D4 (SCH 58235 D4) is the deuterium labeled Ezetimibe
InChiKey: BOZRFEQDOFSZBV-DHIUTWEWSA-N
EL-102 islignan Nesland JMEL102 is a inhibitor of HIF1 , Which can inhibit tubulin polymerisation and decreased microtubule stability. target: HIF1IC 5020 40 nM. in vitro : EL102 is a cytotoxic agent and also displays cytostatic properties, through flow cytometric analysis of PI stained cells cultured for 24, 48 and 72 h, following treatment. EL102 induces apoptosis and causes G2 M arrest, preventing the cell from entering into mitosis. In vivo: CWR22 tumours were taken from
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