PIM-447 dihydrochloride - CAS# 1820565-69-2 Catalog No.:M16461-C 18)12-5-1-3-10-4-2-8-16-13(10)12/h1-6

18)12-5-1-3-10-4-2-8-16-13(10)12/h1-6

extended survival

Smiles: CC(=O)N[C@H]1[C@H](NC(=O)C[C@H](NC(=O)OCC2C3=CC=CC=C3C3=CC=CC=C32)C(O)=O)O[C@H](COC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O

TAS-116 has moderate terminal elimination half-life (t1/2=8

Formula: C14H9Cl3

PIM-447 dihydrochloride - CAS# 1820565-69-2 Catalog No.:M16461-C 18)12-5-1-3-10-4-2-8-16-13(10)12/h1-6PIM447 dihydrochloride (LGH447 dihydrochloride) is a potent, orally available, and selective pan PIM kinase inhibitor, with Ki values of 6, 18, and 9 pM for PIM1, PIM2, and PIM3, respectively. PIM447 dihydrochloride displays dual antimyeloma and bone protective effects. PIM447 dihydrochloride induces apoptosis. Product information CAS Number: 1820565 69 2 Molecular Weight: 513. 38 Formula: C24H25Cl2F3N4O Chemical Name: N {4 [(1R,3S,5S) 3 amino 5