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with response peaking between 15 and 30 minutes after dosing
InChi: InChI=1S/C19H15Cl2N3O2/c1-12-10-18(26-24-12)17(11-22-15-6-2-13(20)3-7-15)19(25)23-16-8-4-14(21)5-9-16/h2-11
Avatrombopag hydrochloride (0-3 μM) induces tyrosine phosphorylation of STAT3 and STAT5
(Z)-Lafutidine shows anti-secretory and gastroprotective activities
InChiKey: IKUFKDGKRLMXEX-UHFFFAOYSA-N
RMC-3943 6243 with response peaking between 15RMC 3943 is an allosteric SHP2 inhibitor (inhibition of full length SHP2 in biochemical assay, IC50 = 2. 19 nM). Product information CAS Number: 1801764 60 2 Molecular Weight: 425. 38 Formula: C18H22Cl2N6S Chemical Name: (1R) 8 {6 amino 5 [(2, 3 dichloropyridin 4 yl)sulfanyl]pyrazin 2 yl} 8 azaspiro[4. 5]decan 1 amine Smiles: NC1=NC(=CN=C1SC1=CC=NC(Cl)=C1Cl)N1CCC2(CCC[C@H]2N)CC1 InChiKey: PSKJCIJLNDJVDV GFCCVEGCSA N InChi: InChI=1S C18H22Cl2N6S c19 14
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