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AM-6494 Size:Contact [email protected] for quotation SI-2 selectively induces breast cancer

SKU: 21542601691

4.0
USD100.00 USD138.00

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Description

SI-2 selectively induces breast cancer cell death with IC50 values in the low nanomolar range (3-20 nM)

4-triazole-3-carboxamide

saline group

Chemical Name: 1-(4-((dimethylamino)methyl)phenyl)-8

InChiKey: VLGATXOTCNBWIT-UHFFFAOYSA-N

AM-6494 Size:Contact [email protected] for quotation SI-2 selectively induces breast cancerAM 6494 is a potent and orally active BACE1 (efficacious site amyloid precursor protein cleaving enzyme 1) inhibitor (IC50=0. 4 nM) with in vivo selectivity over BACE2 (IC50=18. 6 nM). Product information CAS Number: 1874232 80 0 Molecular Weight: 473. 50 Formula: C22H21F2N5O3S Chemical Name: N {3 [(1S,5S,6S) 3 amino 1 (methoxymethyl) 5 methyl 2 thia 4 azabicyclo[4. 1. 0]hept 3 en 5 yl] 4,5 difluorophenyl} 5 (prop 2 yn 1 yloxy)pyrazine 2 carboxamide

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