CC-885 5-IN-1 12a-pentahydroxy-6-methylidene-1

12a-pentahydroxy-6-methylidene-1

2020 Sep 9

In vivo: The upper dose level for once-daily administration of CFI-402257 is between 6 and 6

producing 7 alpha- and 7 beta-hydroperoxides but not 5 alpha-hydroperoxide of cholesterol

3)4)33-24(36)9-7-5-6-8-14-30/h10-13

CC-885 5-IN-1 12a-pentahydroxy-6-methylidene-1CC 885 is a cereblon (CRBN) modulator with potent anti tumour activity. Product information CAS Number: 1010100 07 8 Molecular Weight: 440. 88 Formula: C22H21ClN4O4 Chemical Name: 1 (3 chloro 4 methylphenyl) 3 {[2 (2,6 dioxopiperidin 3 yl) 1 oxo 2,3 dihydro 1H isoindol 5 yl]methyl}urea Smiles: CC1=CC=C(C=C1Cl)NC(=O)NCC1C=CC2=C(CN(C3CCC(=O)NC3=O)C2=O)C=1 InChiKey: DOEVCIHTTTYVCC UHFFFAOYSA N InChi: InChI=1S C22H21ClN4O4 c1 12 2 4 15(9 17(12)23)25