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32(7):967-72
6-tetrahydropyrimidine
+1/p-1/b14-9-
2-oxazole-4-carboxamide
686770-61-6
TAS-103 dihydrochloride Size:Solid 2 mg 32(7):967-72TAS 103, also known as BMS 247615, is a quinoline derivative that displays antitumor activity in murine and human tumor models. TAS 103 has been reported to be a potent topoisomerase II poison. TAS 103 showed the strongest antitumor activity among the conventional anticancer agents for colorectal cancer (p<0. 05). The combination with CDDP augmented the antitumor activity of TAS 103 (p<0. 05), indicating that CDDP is one of the most potent candidates
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