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19-difluoro-11-hydroxy-6
Smiles: O=C(NC1C=C2C(=NNC2=CC=1)C1C=CN=CC=1)[C@H]1CN(CC(=O)N2CCN(CC2)C2C=CC(=CC=2)C2N=CC=CN=2)CC1
MCC950 reduced interleukin-1β (IL-1β) production in vivo and attenuated the severity of experimental autoimmune encephalomyelitis (EAE)
Epub 2015 Dec 7
InChiKey: OONFNUWBHFSNBT-HXUWFJFHSA-N
BMN-673 - CAS# 1207456-01-6 Catalog No.:M10147-2 19-difluoro-11-hydroxy-6BMN 673, also known as Talazoparib and MDV 3800, is an orally bioavailable inhibitor of the nuclear enzyme poly(ADP ribose) polymerase (PARP) with potential antineoplastic activity (PARP1 IC50 = 0. 57 nmol L). Product information CAS Number: 1207456 01 6 Molecular Weight: 380. 35 Formula: C19H14F2N6O Synonym: Talazoparib BMN673 BMN 673 Chemical Name: (11S,12R) 7 fluoro 11 (4 fluorophenyl) 12 (1 methyl 1H 1,2,4 triazol 5 yl) 2,3,10 triazatricyclo[7. 3.