77(5):997-1003
Inhibits locomotor activity in mice expressing hM3Dq and hM4Di in D1-expressing neurons
InChi: InChI=1S/C29H42N2O3S/c1-4-6-8-9-10-11-12-13-21-34-25-17-14-23(15-18-25)29(33)31-26-22-24(16-19-27(26)35-3)28(32)30-20-7-5-2/h14-19
44S)-21-amino-13-(carbamoylmethyl)-27-(2-carboxyethyl)-44-[(1R)-1-hydroxyethyl]-30-[(4-hydroxyphenyl)methyl]-4-methyl-3
GDC-0449-a potent inhibitor of the hedgehog pathway
N-Me-L-Ala-maytansinol 4 dihydrochloride 77(5):997-1003N Me L Ala maytansinol is a hydrophobic, cell permeable payload used for making antibody drug conjugate (ADC). Product information CAS Number: 77668 69 0 Molecular Weight: 650. 16 Formula: C32H44ClN3O9 Chemical Name: (1S, 2R, 3S, 5S, 6S, 20R, 21S) 11 chloro 21 hydroxy 12, 20 dimethoxy 2, 5, 9, 16 tetramethyl 8, 23 dioxo 4, 24 dioxa 9, 22 diazatetracyclo[19. 3. 1. 1, . 0, ]hexacosa 10, 12, 14(26), 16, 18 pentaen 6 yl (2S) 2 (methylamino)propanoate