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InChi: InChI=1S/C14H13N3O4S2/c1-8-7-15-14(22-8)16-13(19)11-12(18)9-5-3-4-6-10(9)23(20
In the rat mGlu4 PAM in vitro assay the EC50 of TCN238 (Compound 11) is 1 μM which is comparable to the human assay
this combination treatment is effective in bortezomib-resistant cells and in the presence of bone marrow stromal cells
significantly inhibits the ability of trichomonads to secrete LTB4 compared to results for trichomonads treated with medium
654671-78-0 (Sitagliptin Phosphate)
CX-5461 dihydrochloride Catalog No.:M14526-2 InChi: InChI=1S/C14H13N3O4S2/c1-8-7-15-14(22-8)16-13(19)11-12(18)9-5-3-4-6-10(9)23(20CX 5461 dihydrochloride is a potent and orally bioavailable inhibitor of Pol I mediated rRNA synthesis, with IC50s of 142 nM in HCT 116, 113 nM in A375, and 54 nM in MIA PaCa 2 cells, and shows little or no effect on Pol II (IC50 25 M). Product information Molecular Weight: 586. 54 Formula: C27H29Cl2N7O2S Chemical Name: 4 (4 methyl 1,4 diazepan 1 yl) N [(5 methylpyrazin 2 yl)methyl] 8 oxo 11 thia 1,3 diazatetracyclo[8. 7. 0. 0,. 0,]heptadeca
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