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The results of hypotensive potency in rats show that both L-765314 and terazosin tend to decrease heart rate (about 25 bpm at 1 mg/kg iv)
RG2833 (RGFP109) could be dosed to KIKI mice by subcutaneous injection at 150 mg/kg
leading to a significant down-regulation of p21
is a farnesyltransferase inhibitor that is being investigated in patients 65 years of age and older with newly diagnosed acute myeloid leukemia (AML)
PubMed PMID: 25727520
Mal-PEG4-Boc Catalog No.:M26940-C The results of hypotensive potencyMal PEG4 Boc is a PEG based PROTAC linker that can be used in the synthesis of PROTACs. Product information CAS Number: 518044 36 5 Molecular Weight: 401. 45 Formula: C19H31NO8 Chemical Name: tert butyl 1 (2,5 dioxo 2,5 dihydro 1H pyrrol 1 yl) 3,6,9,12 tetraoxapentadecan 15 oate Smiles: CC(C)(C)OC(=O)CCOCCOCCOCCOCCN1C(=O)C=CC1=O InChiKey: IYFQIVYGXSVHRQ UHFFFAOYSA N InChi: InChI=1S C19H31NO8 c1 19(2,3)28 18(23)6 8 24 10 12 26 14 15 27 13 11 25 9 7 20
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