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4)20-29(71)28-10-11-36-68(7)14-13-37(67(5
is a novel dual PI3K/mTOR inhibitor with an IC50 ~1 nM
Mice treated with Met or Tmp had decreased PR and QTc intervals and increased heart rates compared to peroral vehicle (VEH)
CAS Number: 752-56-7
12682-12687
ARP 101 Catalog No.:M23013-C 4)20-29(71)28-10-11-36-68(7)14-13-37(67(5ARP 101 is a selective MMP 2 inhibitor with IC50 value of 0. 81nM. MMP 2 is an enzyme and involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction and tissue remodeling, as well as in disease processes, such as arthritis and metastasis . ARP 101 shows inhibition of fibrosarcoma HT1080 cell growth in vitro. ARP 101 has shown ~250 fold selectivity of MMP 2 over MMP 1 and ~100 fold
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